diff --git a/CHANGES.md b/CHANGES.md
index ce3b0adae5..652f4b7955 100644
--- a/CHANGES.md
+++ b/CHANGES.md
@@ -1,3 +1,12 @@
+Synapse 1.43.0 (2021-09-21)
+===========================
+
+This release drops support for the deprecated, unstable API for [MSC2858 (Multiple SSO Identity Providers)](https://github.com/matrix-org/matrix-doc/blob/master/proposals/2858-Multiple-SSO-Identity-Providers.md#unstable-prefix), as well as the undocumented `experimental.msc2858_enabled` config option. Client authors should update their clients to use the stable API, available since Synapse 1.30.
+
+The documentation has been updated with configuration for routing `/spaces`, `/hierarchy` and `/summary` to workers. See [the upgrade notes](https://github.com/matrix-org/synapse/blob/release-v1.43/docs/upgrade.md#upgrading-to-v1430) for more details.
+
+No significant changes since 1.43.0rc2.
+
 Synapse 1.43.0rc2 (2021-09-17)
 ==============================
 
@@ -10,8 +19,6 @@ Bugfixes
 Synapse 1.43.0rc1 (2021-09-14)
 ==============================
 
-This release drops support for the deprecated, unstable API for [MSC2858](https://github.com/matrix-org/matrix-doc/blob/master/proposals/2858-Multiple-SSO-Identity-Providers.md#unstable-prefix), as well as the undocumented `experimental.msc2858_enabled` config option. Client authors should update their clients to use the stable API, available since Synapse 1.30.
-
 Features
 --------
 
diff --git a/debian/changelog b/debian/changelog
index 7774cad55b..4b07d04128 100644
--- a/debian/changelog
+++ b/debian/changelog
@@ -1,3 +1,9 @@
+matrix-synapse-py3 (1.43.0) stable; urgency=medium
+
+  * New synapse release 1.43.0.
+
+ -- Synapse Packaging team <packages@matrix.org>  Tue, 21 Sep 2021 11:49:05 +0100
+
 matrix-synapse-py3 (1.43.0~rc2) stable; urgency=medium
 
   * New synapse release 1.43.0~rc2.
diff --git a/synapse/__init__.py b/synapse/__init__.py
index c9ef90ccaa..5f5cff1dfd 100644
--- a/synapse/__init__.py
+++ b/synapse/__init__.py
@@ -47,7 +47,7 @@ try:
 except ImportError:
     pass
 
-__version__ = "1.43.0rc2"
+__version__ = "1.43.0"
 
 if bool(os.environ.get("SYNAPSE_TEST_PATCH_LOG_CONTEXTS", False)):
     # We import here so that we don't have to install a bunch of deps when