diff --git a/synapse/replication/slave/storage/devices.py b/synapse/replication/slave/storage/devices.py
index 61557665a7..c9f99a8405 100644
--- a/synapse/replication/slave/storage/devices.py
+++ b/synapse/replication/slave/storage/devices.py
@@ -56,6 +56,7 @@ class SlavedDeviceStore(EndToEndKeyWorkerStore, DeviceWorkerStore, BaseSlavedSto
 
     def _invalidate_caches_for_devices(self, token, user_id, destination):
         self._device_list_stream_cache.entity_has_changed(user_id, token)
+        self._user_signature_stream_cache.entity_has_changed(user_id, token)
 
         if destination:
             self._device_list_federation_stream_cache.entity_has_changed(
diff --git a/synapse/storage/data_stores/main/__init__.py b/synapse/storage/data_stores/main/__init__.py
index b185ba0b3e..2d8814f4a7 100644
--- a/synapse/storage/data_stores/main/__init__.py
+++ b/synapse/storage/data_stores/main/__init__.py
@@ -139,7 +139,10 @@ class DataStore(
             db_conn, "public_room_list_stream", "stream_id"
         )
         self._device_list_id_gen = StreamIdGenerator(
-            db_conn, "device_lists_stream", "stream_id"
+            db_conn,
+            "device_lists_stream",
+            "stream_id",
+            extra_tables=[("user_signature_stream", "stream_id")],
         )
         self._cross_signing_id_gen = StreamIdGenerator(
             db_conn, "e2e_cross_signing_keys", "stream_id"
diff --git a/synapse/storage/data_stores/main/devices.py b/synapse/storage/data_stores/main/devices.py
index f7a3542348..a96f09ea7b 100644
--- a/synapse/storage/data_stores/main/devices.py
+++ b/synapse/storage/data_stores/main/devices.py
@@ -543,9 +543,20 @@ class DeviceWorkerStore(SQLBaseStore):
             LEFT JOIN device_lists_outbound_pokes USING (stream_id, user_id, device_id)
             WHERE ? < stream_id AND stream_id <= ?
             GROUP BY user_id, destination
+            UNION
+            SELECT MAX(stream_id) AS stream_id, from_user_id AS user_id, NULL AS destination
+            FROM user_signature_stream
+            WHERE ? < stream_id AND stream_id <= ?
+            GROUP BY user_id
         """
         return self._execute(
-            "get_all_device_list_changes_for_remotes", None, sql, from_key, to_key
+            "get_all_device_list_changes_for_remotes",
+            None,
+            sql,
+            from_key,
+            to_key,
+            from_key,
+            to_key,
         )
 
     @cached(max_entries=10000)